I would avoid anything that dramatically spikes Dopamine. If you're worried about mania as well (Schiz, schiz affective, OCD, Bipolar and I think even autism are link genetically so if one person in your family gets one you've got a higher chance of getting one of those conditions) I would avoid anything that dramatically elevates mood, I think this is serotonin spiking compounds (if not spiking it'll be ones that lower it, but I think I have it the right way). If you're wanting to try a compound that spike dopamine or Serotonin I would try ramping it up slowly and seeing if you feel weird. The only problem with mania is you won't feel like there's anything wrong, but it can also lead to a psychotic break. (It's loads of fun before hand and having the "good" mania is actually really bad LOL. Bloody double edge swords.