Testosterone is a sex hormone; It is naturally produced in both men and women but is made at a much higher level in men. Low testosterone is not just about libido or becoming stronger and bigger in the gym. While this can be an effect of treatment, the condition known as Low T is much more in-depth. It is what gives a male the secondary sex characteristics of a man. Testosterone – which can profoundly reduce energy levels – is responsible for stimulating muscle growth, achieving normal erectile and cognitive functions, restore energy levels and maintaining normal bone density.
For both men and women, an alternative to testosterone replacement is low-dose clomifene treatment, which can stimulate the body to naturally increase hormone levels while avoiding infertility and other side effects that can result from direct hormone replacement therapy.  This therapy has only been shown helpful for men with secondary hypogonadism. Recent studies have shown it can be safe and effective monotherapy for up to 2 years in patients with intact testicular function and impaired function of the HPTA( http:///ijir/journal/v15/n3/full/ ). Clomifene blocks estrogen from binding to some estrogen receptors in the hypothalamus, thereby causing an increased release gNRH and subsequently LH from the pituitary. Clomifene is a Selective Estrogen Reuptake Modulator (SERM). Generally clomifene does not have adverse effects at the doses used for this purpose. Clomifene at much higher doses is used to induce ovulation and has significant adverse effects in such a setting.