Testosterone is secreted by the

Each sperm produced by the testes takes about seventy-two days to mature and its maturity is overseen by a complex interaction of hormones. The scrotum has a built-in thermostat that keeps the testes and sperm at the correct temperature. It may be surprising that the testes should lie in such a vulnerable place outside the body, but it is too hot for them inside. Spermatogenesis requires a temperature that is three to five degrees Fahrenheit below body temperature. If it becomes too cool on the outside, the cremaster muscle will contract to bring the testes closer the body for warmth.

Transdermal patches (adhesive patches placed on the skin) may also be used to deliver a steady dose through the skin and into the bloodstream. Testosterone-containing creams and gels that are applied daily to the skin are also available, but absorption is inefficient (roughly 10%, varying between individuals) and these treatments tend to be more expensive. Individuals who are especially physically active and/or bathe often may not be good candidates, since the medication can be washed off and may take up to six hours to be fully absorbed. There is also the risk that an intimate partner or child may come in contact with the application site and inadvertently dose himself or herself; children and women are highly sensitive to testosterone and can suffer unintended masculinization and health effects, even from small doses. Injection is the most common method used by individuals administering AAS for non-medical purposes. [45]

Testosterone is secreted by the

testosterone is secreted by the


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