Undecylenic acid mechanism of action

Fungi will often cause the area around the nail to become red and irritated. Initially a fungus will take hold at the base or edges of the nail. Once the infection continues to spread you'll notice changes in your nail and nail bed. You may experience mild discomfort, itching, or perhaps even sharp pain around the cuticle which is the skin surrounding the nail. Bleeding may begin to occur and often detachment from the cuticle to the nail may result. The nail will begin a slow transformation to perhaps a yellow, brown, or white coloration. Nails will often become thicker and extremely brittle. You may experience discomfort when you put weight on any fungal infected nail.

There are also many drug interactions . Patients must read in detail the enclosed data sheet(s) of the medicine. For example, the azole antifungals such as ketoconazole or itraconazole can be both substrates and inhibitors of the P-glycoprotein , which (among other functions) excretes toxins and drugs into the intestines. [20] Azole antifungals also are both substrates and inhibitors of the cytochrome P450 family CYP3A4 , [20] causing increased concentration when administering, for example, calcium channel blockers , immunosuppressants , chemotherapeutic drugs , benzodiazepines , tricyclic antidepressants , macrolides and SSRIs .

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Undecylenic acid mechanism of action

undecylenic acid mechanism of action

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